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In the realm of medical diagnostics, the Coombs test stands as a crucial tool in identifying and understanding various autoimmune diseases, particularly those involving the destruction of red blood cells. Among its iterations, the Indirect Coombs Test (ICT) holds significant importance in the diagnosis of conditions such as autoimmune hemolytic anemia (AIHA), hemolytic disease of the newborn (HDN), and drug-induced hemolytic anemia. This article delves into the intricacies of the Indirect Coombs Test, shedding light on its principl... more