The epidermal growth factor receptor (EGFR) is a protein that plays a crucial role in cell growth, division, and survival. It belongs to the ErbB family of receptors, which also includes HER2, HER3, and HER4. EGFR is a transmembrane glycoprotein composed of an extracellular ligand-binding domain, a transmembrane domain, and an intracellular tyrosine kinase domain. Its activation triggers a complex signaling network that regulates various cellular processes, including proliferation, differentiation, migration, and apoptosis.EGFR ...
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