Vidalista 60 mg contains the active ingredient tadalafil, which belongs to a class of medications called phosphodiesterase type 5 (PDE5) inhibitors. Here's how Vidalista 60 mg works to treat erectile dysfunction (ED): Nitric Oxide Release: Sexual stimulation triggers the release of nitric oxide (NO) in the erectile tissue of the penis. cGMP Production: Nitric oxide activates an enzyme called guanylate cyclase, which increases the levels of cyclic guanosine monophosphate (cGMP) in the smooth muscle cells of the penile arteries and corpus cavernosum (erectile tissue). Smooth Muscle Relaxation: Elevated levels of cGMP cause the smooth muscle cells in the penile blood vessels to relax, allowing them to dilate (widen). This relaxation and dilation increase blood flow to the penis. Erection Formation: The increased blood flow fills the erectile chambers (corpora cavernosa) of the penis, resulting in an erection. This erection is maintained as long as there is sexual stimulation and sufficient levels of cGMP. PDE5 Inhibition: Tadalafil in Vidalista 60 Mg works by inhibiting the action of phosphodiesterase type 5 (PDE5), an enzyme that breaks down cGMP. By blocking PDE5, tadalafil helps to maintain higher levels of cGMP in the erectile tissue, prolonging the effects of nitric oxide and smooth muscle relaxation. Enhanced Erectile Response: By increasing blood flow to the penis and promoting smooth muscle relaxation, Vidalista 60 mg helps men achieve firmer and longer-lasting erections, improving their ability to engage in sexual activity. It's important to note that Vidalista 60 mg does not cause spontaneous erections. Sexual stimulation is still required for the medication to be effective. Additionally, Vidalista 60 mg is not a cure for ED but rather a treatment that helps manage the symptoms of the condition. Vidalista 60 mg should be taken as directed by a healthcare provider, typically about 30 minutes to 1 hour before sexual activity. It's essential to follow the recommended dosage and administration instructions to ensure safe and effective use of the medication.