Fildena CT 50 mg, containing Sildenafil Citrate, is not recommended for individuals with severe renal impairment due to the following reasons:
Altered Drug Metabolism and Excretion: The kidneys play a crucial role in the excretion of Fildena CT 50 mg and its metabolites. In individuals with severe renal impairment, the ability to clear the drug from the body is significantly reduced, leading to higher concentrations of the drug in the bloodstream and potentially increasing the risk of side effects.
Increased Risk of Adverse Effects: Higher levels of Sildenafil in the body can increase the likelihood of experiencing adverse effects such as headaches, dizziness, hypotension (low blood pressure), and prolonged erections (priapism). These risks are heightened in individuals with compromised kidney function.
Potential for Accumulation: With severe renal impairment, there is a risk of drug accumulation with repeated doses. This can lead to toxicity and exacerbate side effects, making it unsafe for regular use without close monitoring.
Existing Health Complications: Individuals with severe renal impairment often have other underlying health conditions, which can further complicate the use of medications like Sildenafil. The interplay between multiple health issues and medications requires careful management and monitoring.
Dosage Adjustments and Monitoring: In cases of mild to moderate renal impairment, healthcare providers may adjust the dosage and closely monitor the patient to mitigate risks. However, for severe renal impairment, the risks often outweigh the benefits, and alternative treatments are typically preferred.
Due to these concerns, it is essential for individuals with severe renal impairment to consult with a healthcare provider to explore safer and more appropriate treatment options for erectile dysfunction.