Avana, a brand name for the drug avanafil, is used primarily to treat erectile dysfunction (ED). As with many medications, avanafil can interact with other drugs, which can potentially affect its efficacy or increase the risk of adverse effects. Here are some key interactions to be aware of:
Nitrates: Combining Avana with nitrates (such as nitroglycerin or isosorbide) can cause a significant drop in blood pressure. This combination can lead to dizziness, fainting, or even a heart attack. It's important to avoid using avanafil if you are on nitrates or have recently used them.
Alpha-blockers: Medications used to treat high blood pressure or prostate problems (like doxazosin or tamsulosin) can interact with avanafil. This combination might lead to a drop in blood pressure or cause dizziness. It's essential to monitor blood pressure closely and consult a healthcare provider before combining these treatments.
Other ED Medications: Using avanafil alongside other erectile dysfunction medications (like sildenafil, tadalafil, or vardenafil) is not recommended. This can increase the risk of side effects and is generally not advised.
Antifungal Medications: Certain antifungals, like ketoconazole or itraconazole, can increase the levels of avanafil in the blood, potentially leading to an increased risk of side effects.
HIV Protease Inhibitors: Drugs used to treat HIV (such as ritonavir) can also raise avanafil levels in the blood, which may increase the risk of adverse effects.
Certain Antibiotics: Some antibiotics, such as clarithromycin, may affect how avanafil is metabolized, potentially leading to an increased risk of side effects.
Other Medications: Some medications, such as certain anticonvulsants or medications that affect liver enzymes, can interact with avanafil.
Always consult with your healthcare provider before starting or combining medications, including over-the-counter drugs and supplements. Your provider can help assess potential interactions and adjust your treatment plan as needed.
